Pick-Ups

Pick-Ups refer to any Item that can be picked up without taking up a slot.

Bombs[]

Bombs are a consumable Item that can be infinitely stacked.

Bombs are placed on the tile the player is standing on and after 4 beats explodes in a 3x3 area centered on the bomb. The explosion has the following effects:

Destroys Walls, Traps, Items (except the Golden Lute) and gold piles.
Removes Water and Conduits and turns Ice into Water.
Deals 4 damage to enemies and 2 hearts of damage to the player.
Opens crates and barrels, damages Teh Urn, and destroys all types of Gargoyle.
Can damage all Mimics and Fake Walls even before they are active.

Bombs can be accessed by pressing Down + Left, or the left trigger button on console. (As Diamond, press Up + Down instead.)

Blast Helm - Bombs are instantly detonated and do not damage the player.
Grenade Charm - Bombs are instantly thrown 3 tiles away from the player and explode in 2 beats. The player's Bombs also deal +2 damage to enemies and +1 heart of damage to the player.
Bomb Charm - Bombs explode in a 5x5 area and do not harm player characters.

Item	Effects
Bomb	Gives the player 1 Bomb.
3 Bombs	Gives the player 3 Bombs.
Grenade	Held Bombs take this appearance while the player is holding a Grenade Charm

Heart Containers[]

See: Health

Heart Containers are added to the player's Health when collected. The player can have a maximum of 10 Hearts at once.

Item	Effects
Filled Heart Container	Adds 1 Heart Container to the player's Health. Converts Cursed Heart to Heart Container if having 10 Heart Containers in total. Converts empty Heart Container to Heart Container if having 10 Heart Containers in total and no Cursed Heart.
Double Filled Heart Container	Adds 2 Heart Containers to the player's Health. Converts Cursed Heart to Heart Container if having 10 Heart Containers in total. Converts empty Heart Container to Heart Container if having 10 Heart Containers in total and no Cursed Heart.
Empty Heart Container	Adds 1 empty Heart Container to the player's Health. Converts Cursed Heart to Heart Container if having 10 Heart Containers in total.
Double Empty Heart Container	Adds 2 empty Heart Containers to the player's Health. Converts Cursed Heart to Heart Container if having 10 Heart Containers in total.
Cursed Heart Container	Adds 1 Cursed Heart to the player's Health. No effect if having 10 Heart Containers in total.
Double Cursed Heart Container	Adds 2 Cursed Hearts to the player's Health. No effect if having 10 Heart Containers in total.

Keys[]

Keys are unique to single-zone gamemodes. They are used to unlock various things.

Item	Effects
Key	Used to open Locked Chests and Locked Doors.
Golden Key	Used to open a Golden Cage, freeing an NPC and unlocking their room in the Lobby.
Glass Key	Used to open a Glass Cage, freeing an NPC and unlocking their room in the Lobby. Breaks if the player takes damage.

Charms[]

Charms are worn by the player and provide various effects.

Item	Effects
Strength Charm	Increases attack damage by 1.
Risk Charm	When the player is at 0.5 Health remaining, Risk Charm increases attack damage by 2.
Protection Charm	Adds +0.5 Defense.
Nazar Charm	Removes all Spirits from the floor.
Gluttony Charm	Upon consuming a Food Item that would restore more Health than the player has Empty Hearts for, Gluttony Charm adds 1 Filled Heart Container for each Heart of healing past capacity. Gluttony Charm is consumed in the process. Does not consumed when eating magic food.
Frost Charm	Prevents all damage from one hit, then breaks. Upon breaking, it casts Freeze, freezing all enemies within 5 tiles for 8 beats.
Lucky Charm	Increases the floor's item tier by 1, increasing the chance of finding higher-tiered items in containers and shops. Prevents Bats from attacking the player (unless they have no other movement option), this applies to both players in local co-op. Guarantees success when using the Shrine of Chance, this only applies to the equipping player in local co-op. When entering new floors, barrels and crates with Food or Bombs contain a better version of it.
Bomb Charm	Bombs explode in an area of 5x5 tiles. The player's Bombs do not harm player characters.
Grenade Charm	All held Bombs become Grenades. Grenades are instantly thrown 3 tiles away from the player and explode in 2 beats. The player's Bombs deal +2 damage to enemies and +1 heart of damage to the player. Gives 3 Bombs when picked up for the first time. Only available in the Level Editor.

Miscellaneous[]

All other pickups that don't fit into the above categories are listed below.

Item	Effects
Map	Reveals the floor's layout, including the locations of Chests on the floor.
Compass	Reveals the location of the Exit Stairs. When the Exit Stairs are out of view, a blue arrow appears on the HUD that points towards it.
Coupon	The next Item the player buys from any Shop is sold for free. The Coupon is consumed in the process.
Potion	Upon losing all Health, the Potion instantly refills the player's Health. The Potion is consumed in the process. Does not revive the player if they die from Cowardice, Vow of Poverty, Mary's Curse or Tempo's Curse.
Monkey's Paw	All types of Monkeys, Water Balls and Gorgons become permanently frozen.